To our knowledge, this is the first reported study in which we examine the relationship between SUVmax and phosphorylated-Akt (Ser-473) (pAkt (Ser-473), phosphorylated-Akt (Thr-308) (pAkt (Thr-308), and phosphorylated-S6 ribosomal protein (Ser-235/236) (pS6) expression levels in human RCC. The gene discussed is AKT1; the disease is renal cell adenocarcinoma.