RGS1 and aneurysm: Our study now reveals that Rgs1 is specifically upregulated in monocytes and macrophages by inflammatory stimuli, indicating that Rgs1 expression is high in the recruited cells that contribute to plaque formation and/or is further upregulated in the cells within the fatty-streak lesions or aneurysms of ApoE−/− mice, and in human aneurysms.