The interleukin 6 receptor gene (IL6R) region centered at rs8192284A/C, a functional SNP causing a Asp358Ala aminoacid change in the membrane bound IL6R, has been associated with the risk of coronary heart disease (CHD) [1–4], as well as with serum levels of inflammatory biomarkers. The gene discussed is IL6R; the disease is coronary artery disorder.