The results indicated that the loss of plexin-B3 expression was associated with the patient gender (P=0.01, χ2 test; Table II) and tumor size (P=0.001, χ2; Table II); however, there were no correlations with age, histology, tumor stage, tumor number, capsule invasion, microvascular invasion and liver cirrhosis (Table II). This evidence concerns the gene PLXNB3 and neoplasm.