ANGPT1 and fetal growth restriction: Our analysis revealed a weak association between Ang-1 and Ang-2 in the PE-IUGR group and no significant correlation was observed between these parameters in the control and the PE group, in accordance with the study by Han et al. These findings are in line with those of earlier reports that support an excess of circulating levels of anti-angiogenic factors even before the clinical manifestation of PE (2,49).