TG and obesity due to melanocortin 4 receptor deficiency: FT4 was lower in patients with HDL ≤ 40 mg/dl compared with those with HDL > 40 mg/dl 17.8 ± 0.3 vs 18.9 ± 0.3 p < 0.048 There were no difference in thyroid hormone or TSH concentration classifying by metabolic syndrome or the rest of their components or categorizing by overweight or obesity (data not shown).