In contrast to previous findings obtained from human breast cancer, which indicated that Wnt5a mRNA level and protein level are not coordinately regulated in same tissue sample [30, 31], we noticed that gastric cancer SGC-7901 cells are continuously expressing high levels of Wnt5a mRNA and protein, both of which were suppressed by EGF in the present study. The gene discussed is WNT5A; the disease is breast cancer.