TLR7 and acute myeloid leukemia: Noteworthy down-regulated genes included members of LILR family (LILRB1, LILRB3, LILRB4, LILRA1, LILRA2, LILRA6), members of TLR family (TLR2, TLR4, TLR5, TLR7) and the immune molecule CD86, which indicated the possible mechanisms of immune evasion that led to the worse outcome for CN-AML patients with high ITPR2 expression.