The presence of RCAS1 in the tumor is responsible for the process of tumor escape from host immunological surveillance by the inhibition of the growth and the induction of the apoptosis of T and B lymphocytes and NK cells (Sonoda et al. 1996, 2005, 2006, 2008, 2009; Sonoda 2011). This evidence concerns the gene EBAG9 and neoplasm.