ANGPTL2 and breast neoplasm: In the present study, we performed RNA sequence analysis of MDA-MB231 cells harboring ANGPTL2 knockdown (MB231/miANGPTL2) and found that, relative to control (MB231/miLacZ) cells, CXCR4 expression significantly decreased, suggesting that ANGPTL2 contributes to CXCR4 expression in breast tumor cells.