CD34 and disease arising from reactivation of latent virus: Consistent with this, and the known increase in cIL-10 during HCMV latent infection of CD34+ cells [32], latently infected CD34+ cells also showed extensive increases in STAT3 phosphorylation (Fig. 2b, c) and concomitant increases in the expression of Bcl2 and HSP70 (Fig. 2a, c).