Detailed analysis of the mechanism by which latency-associated changes in hsa-miR-92a were linked to GATA2 expression and subsequent regulation of cIL-10 came from studies in KG1 cells, a CD34+ cell line which can be manipulated by transfection and recapitulate some aspects of HCMV latent infection, namely the expression of latency-associated genes such as UL138 in the absence of lytic immediate early gene expression [31]. This evidence concerns the gene CD34 and disease arising from reactivation of latent virus.