We have translated the embryological and genetic studies of exocrine pancreas organogenesis in zebrafish into identification of the TRPM7 ion channels in human pancreatic adenocarcinoma (Yee et al., 2012a; Yee and Yee, 2013; Yee et al., 2012b; Yee et al., 2011). This evidence concerns the gene TRPM7 and pancreatic adenocarcinoma.