TRPM7 and pancreatic adenocarcinoma: In an attempt to understand the mechanism underlying the aberrant over-expression of TRPM7 in pancreatic adenocarcinoma, we analyzed genomic TRPM7 by quantitative real-time PCR using primers directed against the sequence within intron 16 of TRPM7. We found that TRPM7 DNA in the genome of three pancreatic adenocarcinoma cell lines previously shown to express elevated levels of TRPM7 mRNA is not amplified relative to non-cancerous pancreatic ductal epithelia (Yee, N.S., data not shown).