IFNG and infection: Consistent with the infection experiments, feeding OTII(dnRara)-recipient mice OVA resulted in a shift in the Th1-Th17-cell balance with a deficiency in IFN-γ-producing cells and increased frequency of IL-17+ and dual IFN-γ+IL-17+ cells in the mesenteric lymph node (MLN), lamina propria lymphocytes (LPL), and spleen (Sp), 7 days after transfer (Figures 7B and 7C).