The mRNA level of BDNF was significantly lower in autistic sera treated rat brains compared to sham and control sera treatment groups (Fig. 6G; ANOVA, p = 0.0006; sham vs. autism group, Bonferroni’s post-hoc test, p<0.01; autism serum vs. control serum group, Bonferroni’s post-hoc test, p<0.01). This evidence concerns the gene BDNF and autism.