As depicted by the leftward deviation of the dotted lines in the QQ-plots for CAD (p = 1.4×10-09), the cholesterol phenotypes (HDL-cholesterol, p = 6.4×10-69; LDL-cholesterol, p = 2.9×10-166; total cholesterol, p = 3.6×10-169 and triglycerides, p = 2.5×10-196) and the glycemic phenotypes (fasting glucose, p = 2.4×10-12 and fasting insulin 5.5×10-04), the p-values for the association between the 18 CRP SNPs and these phenotypes are significantly smaller than expected under the null hypothesis (Fig. 2). Here, INS is linked to coronary artery disorder.