Boullier et al. showed similar levels of IgG-LDL immune complexes in patients with coronary artery disease and controls, and Festa et al. decreased anti-oxidized LDL IgG in patients with long duration of type 1 diabetes and high HbA1c levels compared to controls, whereas Karvonen et al, demonstrated an inverse relation between anti-oxidized LDL IgM and carotid artery atherosclerosis [33, 34, 36]. Here, CD40LG is linked to type 1 diabetes mellitus.