A population based case-control study carried out on 18 SNPs within PKM2 gene, including 15 intronic and 3 in the neighbouring UTR regions (2 close to 5’UTR and 1 close 3’UTR) in 205 sporadic breast cancer cases and 183 controls from northern India (Table 5), showed only 5 intronic SNPs (rs8192386, 0.029; rs1037680, 0.043; rs8192431, 0.053; rs2856929, 0.062; rs8192381, 0.088) in strong association with breast cancer (Table 5). This evidence concerns the gene PKM and breast cancer.