SLC2A5 and plasma cell myeloma: To further investigate the impact of SLC2A5 gene overexpression, in 2010 Inoue and collaborators reported that cells derived from human myeloma overexpressing GLUT5 were able to achieve more than 1.5 times the cell density reached by wild-type cells and produce more than 2 times the amount of recombinant protein [14].