GDF15 and neoplasm: There was again no correlation in expression between matched tissues (r = 0.12) and in non-matched cases, the difference between tumor and disease-free tissues (p(t)<0.001; p(WRS)<0.05), and between tumor adjacent and disease-free tissues (p(t)<0.001; p(WRS)<0.001) remained significant, while MIC-1 expression in tumor and tumor-adjacent tissues (p(t) = 0.69; p(WRS) = 0.56) was similar (Fig. 2D).