Additional SNPs for IBD-associated variants identified in this study and their gene targets—rs6545800 with adenylate cyclase (ADCY3), rs4077515 with inositol polyphosphate 5-phosphatase (INPP5E), rs9858542 with ubiquitin-like modifier activating enzyme 7 (UBA7), and rs678170 with neuroexophilin and PC-esterase domain family member 1 (NXPE1) and with RNA exonuclease 2 (REXO2) —were novel targets and should be validated in a larger study. The gene discussed is NXPE1; the disease is inflammatory bowel disease.