Among 40 patients with gastric cancer, 28 of 40 (70%) samples revealed >50% increase in the RUFY3 level relative to their matched non-tumor adjacent tissues (Figures 6b and c, P=0.003 and Table 1), and PAK1 had high expression as well in most of the gastric cancer tissues, which was consistent with the previous reports on PAK1 expression in cancer cells and gastric cancer samples.18, 20 Moreover, RUFY3 levels in gastric cancer sample were also analyzed and plotted against the level of PAK1. The gene discussed is PAK1; the disease is cancer.