To further investigate the effects of histone H3K9 methyltransferase G9a on the transcription of target genes in leukemia cells, we performed global gene expression profiling with human erythroleukemia K562 cells stably expressing either control shRNA or G9a shRNA in a Tet-on inducible expression system (Supplementary Figure S1C). The gene discussed is EHMT2; the disease is erythroleukemia.