These genes are from several DNA repair pathways: base excision repair (BER, e.g. NEIL2, PARP2 and APEX1), mismatch excision repair (MMR, e.g. PMS2P3), nucleotide excision repair (NER, e.g. ERCC3, XPA, ERCC6, ERCC4 and RPA1), homologous recombination (HR, e.g. XRCC2, GIYD1, GIYD2 and EME1), DNA polymerases, editing and processing nucleases, ubiquitination and modification and Fanconi anemia (Figure 3 and Supplementary Table S5). Here, EME1 is linked to Fanconi anemia.