APP and Alzheimer disease: This was followed by globus pallidus with 9% in AD-iPS5 neurons for the genes APP, ATP2A2, CALM2, CALM3, CDK5, GAPDH and PPP3CB and 9% in AD-iPS26B neurons for the genes APP, ATP2A2, CALM2, CALM3, CDK5 and GAPDH. The percentages for medulla oblongata, prefrontal cortex and amygdala were found to be 5–8% (Figure 4c and d).