Lysozyme M (LysM)-cre MHCII fl/fl (macrophages and granulocytes [25]), BATF3−/− (CD103+ conventional dendritic cells [5]), and CCR2−/− (monocytes and monocyte-derived dendritic cells [26]) mice generated robust antigen-specific Th2 responses during cryptococcal infection (S5–S6 Fig.). The gene discussed is CCR2; the disease is cryptococcosis.