ERBB2 and breast neoplasm: However, in contrast to the enrichment of basal-like or triple-negative tumors observed in previous studies, our results showed that breast tumors from CCSS cases were preferentially of two subtypes: luminal or HER2+, which is in line with what was observed by Castiglioni in breast tumors developed in women irradiated for HL within 4 years of menarche [25].