TP53 and cancer: These results are consistent with results in other tissues, where faf RNAi reduced Prickle levels in Drosophila apicolateral junctions,[33] as well as studies showing USP9X stabilizes several proteins involved in various aspects of neuronal development and cancer.[12] Notably, USP9X was shown to stabilize oncoproteins (e.g., MCL-1 and p53), sparking interest in modulating USP9X in tumors, with promising results.[24]