To determine whether AOM/DSS treatment can induce activation of PI3K/Akt in mouse colonic epithelium (containing extensive adenocarcinoma, foci of adenomatous and dysplastic changes, and normal adjacent epithelium) and the effect of dietary strawberries on the activation, we detected phosphorylation of PI3K, Akt, ERK and NFκB. The gene discussed is AKT1; the disease is adenocarcinoma.