INS and polycystic ovary syndrome: Insulin appears to augment not only StAR expression, but also CYP11A1, 17-α-hydroxylase/17,20-lyase (CYP17A1), 3-β-hydroxysteroid dehydrogenase (3-β-HSD), and aromatase (CYP19A1) expression, contributing to an excess in the production of progesterone, 17-α-hydroxyprogesterone, and testosterone in polycystic ovaries in comparison to healthy ovaries [83].