Mavrakis and collaborators found that miR-19 is highly expressed in ALL and in aggressive B-cell lymphoma; in a single patient with T-ALL, they identified two novel translocations, t(9;14)(q34;q11) and t(13;14)(q32;q11), involving simultaneously Notch1 and the 17–92 cluster including miR-19 (68). The gene discussed is NOTCH1; the disease is acute lymphoblastic leukemia.