Following subcutaneous inoculation of B16 cells, P-sel−/− mice manifested mitigated platelet recruitment (Supplemental Figure 5A), prolonged overall survival (Supplemental Figure 5B) along with reduced tumor volume (Supplemental Figure 5C) and size (Supplemental Figure 5D) in comparison with C57BL/6J mice. This evidence concerns the gene SELP and neoplasm.