GNAS and Globozoospermia: As shown in Table 2, six imprinted genes showed different 5hmC patterns between normal and abnormal sperm (GDAP1L1, GNAS, KCNK9, LIN28B, RB1, RTL1), and five imprinted genes showed different 5hmC patterns between normal and globozoospermia sperm (KCNK9, LIN28B, RB1, SLC22A18, ZDBF2).