EZH2 and diffuse large B-cell lymphoma: We have analyzed EZH2, H3K27me1, H3K27me2 and H3K27me3 IHC expression in relation to EZH2 somatic mutation status in a cohort of patients with DLBCL and shown that a simple IHC experiment is able to distinguish patients with WT EZH2 and patients with EZH2 Y641 mutations according to their me3/me2 score in the majority of cases.