Only a small subset of probes was consistently altered in the 3 GBM cell lines (17 probes upregulated and 40 downregulated due to HOXA9 expression in U87MG, U251 and GBML18 cells), which, as expected, was even smaller when integrating the non-tumor immortalized astrocytes (1 probe upregulated and 3 downregulated; Figure 2B), indicating that the transcriptome of HOXA9 is cell-type dependent, as previously suggested in leukemia models [19]. The gene discussed is HOXA9; the disease is leukemia.