HOXA9 and glioblastoma: In order to provide the first characterization of HOXA9 targets on a genome-wide level in GBM, expression microarray analyses were performed in matched HOXA9-positive and HOXA9-negative human GBM cell models (U87MG-MSCV vs. U87MG-HOXA9, human immortalized astrocytes hTERT/E6/E7-MSCV vs. hTERT/E6/E7-HOXA9, U251-shControl vs. U251-shHOXA9, and a primary GBM cell line GBML18-shControl vs. GBML18-shHOXA9; Figure 2A and 2B).