In the present study, we further observed that allosteric inhibition of mTORC1 by rapamycin suppressed IGF-1-stimulated cell adhesion in a panel of tumor cell lines, including human rhabdomyosarcoma (Rh30), Ewing sarcoma (Rh1), colon carcinoma (HT29), and cervical adenocarcinoma (HeLa) cells, which was not by reducing the cell viability. Here, IGF1 is linked to colon carcinoma.