As shown in Figure 6A, infection of Rh30 cells with lentiviral shRNA to 4E-BP1 resulted in a significant downregulation of 4E-BP1 protein expression compared to control cells infected with lentiviral shRNA to GFP, as detected by Western blotting with antibodies to 4E-BP1. The gene discussed is EIF4EBP1; the disease is infection.