ADAMTSL2 and McLeod neuroacanthocytosis syndrome: Musladin-Lueke syndrome (MLS), a canine non-progressive, non-lethal condition caused by a founder Arg221Cys ADAMTSL2 mutation in beagles (which is identical to a mutation identified in GD), also causes short stature, skin and joint fibrosis with GD, but does not give rise to cardiopulmonary problems (Bader et al., 2010; Allali et al., 2011).