TP53 and osteosarcoma: In an attempt to characterize the mechanism of the p53 regulation of miRNAs, we used publicly available TP53 chromatin immunoprecipitation - sequencing (ChIP-Seq) data from IMR-90 normal lung fibroblast cells and Saos-2 osteosarcoma cells (GEO GSM783262 and GSM501692, respectively).