Our results showed that the presence of TPCA-1 significantly increased the migration capacity of BMSCs from SLE patients both in the cell scratch (384.8824 ± 51.8000 μm versus 466.7647 ± 41.4000 μm, n = 6, P = 0.03) and transwell migration assays (6.47 ± 1.39‰ versus 8.02 ± 1.00‰, n = 6, P = 0.003) (Figure 4(c)), indicating that IKK-β activation participated in impaired migration capacity of SLE BMSCs. This evidence concerns the gene IKBKB and systemic lupus erythematosus.