IKBKB and systemic lupus erythematosus: To elucidate whether TNF-α induced impaired migration capacity of SLE BMSCs was mediated by the activation of IKK-β signaling, p-IKK-β level and migration capacity of SLE BMSCs were measured after culturing in the absence or presence of recombinant human TNF-α together with or without TPCA-1.