STAT3 and cancer: Although miR-601 appears to be a major player in predictive ability of salvage radiation response, miR-4516 and miR-601 together appear to be correlated (Pearson r = 0.56, p-value <0.0001) and target pathways of both STAT3 and NF-kB pathways that are critical regulators of the inflammatory responses in cancer [89].