Interestingly, transfer of HIV-1 particles from IFN-α-DCs to T cells was more susceptible to neutralization by VRC01 and NIH45–46 G54W [IC50 = 0.508 ± 0.155 μg/ml (Fig. 6E and H) and 0.069 ± 0.016 μg/ml (Fig. 6F and I), respectively] than that mediated by LPS-DCs, though efficiency of IFN-α-DC mediated transfer in the presence of VRC01 and NIH45–46 G54W was still greater than that observed for cell-free infection of T cells. This evidence concerns the gene IFNA1 and infection.