However, nuclear expression of p50, which is also indicative of canonical NF-κB pathway activation [32], was significantly decreased in CD5+ ABC-DLBCL (Figure 3E, Table 2), which was not due to the NFKB1 downregulation at the mRNA level (Supplemental Figure 1L). This evidence concerns the gene NFKB1 and diffuse large B-cell lymphoma.