CD5 and diffuse large B-cell lymphoma: CD5+ DLBCL patients had significantly poorer overall survival (OS) (median OS: 25.3 months vs. not reached, hazard ratio [HR]: 3.87, 95% confidence interval [CI] of rate: 1.99-7.51, P < .0001) and progression-free survival (PFS) (median PFS: 21.3 vs. 85.8 months, HR: 4.31, 95% CI: 2.26-8.23, P < .0001) in the training set, regardless of cell-of-origin (COO) (Figures 1D-I).