LTBP1 (functioning in the assembly, secretion, and targeting of TGFβ1 to ECM), INHBA (encoding a TGFβ family member), and PTPRB (involved in blood vessel remodeling and angiogenesis) were downregulated in CD5+ DLBCL. The gene discussed is TGFB1; the disease is diffuse large B-cell lymphoma.