Gene expression profiles of CD5+ and CD5− DLBCL were compared to identify CD5 gene signatures in de novo DLBCL, which showed 86 differentially expressed genes (DEGs) by comparison within the overall cohort, and 39 DEGs by comparison within the ABC-DLBCL subcohort (Figures 5A-B, Table 4). The gene discussed is CD5; the disease is diffuse large B-cell lymphoma.