Documents have demonstrated that several lncRNAs, such as lncRNA HULC, RERT and HOTTIP/HOXA13, etc., are dysregulated in HCC and closely related to tumorigenesis, metastasis, prognosis, diagnosis, and drug resistance [5–7], opening up a new avenue for investigating the occurrence and development molecular mechanisms of HCC. Here, HOXA13 is linked to hepatocellular carcinoma.