Both IL-12 and IFNγ are involved in immunosurveillance against tumor cells [33–36]; likewise, it has been shown that exogenous administration of IL-12 in mice with induced tumors may promote the reduction in tumor size by increasing the activation of CD8+ T lymphocytes, which are responsible for inducing apoptosis in tumor cells [37, 38]. Here, IFNG is linked to neoplasm.