GBA2 and Ataxia: The overlap between HSP and ataxias was again recently highlighted by mutations in GBA2 (SPG46), which have been found in patients with spastic ataxia associated with cataract, having ataxia (Hammer et al. 2013; Votsi et al. 2014) or spasticity (Martin et al. 2013; Citterio et al. 2014) as the prominent clinical feature.