EGFR and ovarian carcinoma: Oxygenation of human A2780 ovarian carcinoma tumors, that are negative for EGFR, xenografted onto the chorioallantoic membrane of chicken embryos was studied following treatment with the anti-angiogenic tyrosine kinase inhibitors (TKIs) axitinib, sunitinib or erlotinib (Fig. 1A).