CASP3 and B-cell chronic lymphocytic leukemia: The Antho 50-induced activation of caspase 3 was inhibited in CLL cells CLL11, 6 and 20 (Fig. 7) and CLL9 and 10 (data not shown) in the presence of PEG-catalase as well as the down-regulation of UHRF1 in CLL11, 6 and 20 (Fig. 7).