PARD6A and non-small cell lung carcinoma: Phosphorylation of Par6, by the TGF-β receptor and aPKC, has been correlated with reduced survival in breast cancer patients, being associated with more invasive tumours and also increased migration of non-small-cell lung cancer (NSCLC) cells (Fig. 2b) (Viloria-Petita et al., 2009; Gunaratne et al., 2013).