CDH2 and cancer: As observed before, treatment with Cyt D leads to the induction of E-cadherin in HT-1080 with concomitant loss of N-cadherin and vimentin at 50 μM Cyt D. Interestingly, treatment with Cyt D on Hs27 did not affect E-cadherin, N-cadherin or vimentin expression suggesting that Cyt D induction of MET is specific to cancer cells (Fig. 6A).