In chronic colitis, colon Cav-1 levels were significantly and inversely correlated with colon inflammatory scores in (P < 0.0003, r = -0.828) (Fig. 4), and also inversely correlated with IL-17 and TNF, but not IFN, levels (P < 0.01; r = -0.641 for IL-17; P < 0.02, r = -0.624 for TNF). This evidence concerns the gene TNF and Chronic colitis.