BRD2 and cardiovascular disorder: (2003) found that premenopausal females with an FSH level ≥ 7 IU L−1 exhibit significantly increased TC and LDL compared with those with FSH < 7 IU L−1; this result suggests that increased FSH levels are correlated with known cardiovascular disease (CVD) risk factors and reveals the critical roles of FSH in lipid metabolism.